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For oth­er kinds of stress see stress. Phys­i­o­log­i­cal or bio­log­i­cal stress is an organ­is­m’s response to a stres­sor such as an envi­ron­men­tal con­di­tion or a stim­u­lus. Stress is a body’s method of react­ing to a chal­lenge. Accord­ing to the stress­ful event, the body’s way to respond to stress is by sym­pa­thet­ic ner­vous sys­tem acti­va­tion which results in the fight-or-flight response. Because the body can­not keep this state for long peri­ods of time, the parasym­pa­thet­ic sys­tem returns the body’s phys­i­o­log­i­cal con­di­tions to nor­mal (home­osta­sis). In humans, stress typ­i­cal­ly describes a neg­a­tive con­di­tion or a pos­i­tive con­di­tion that can have an impact on a per­son­’s men­tal and phys­i­cal well-being.