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The seba­ceous glands are micro­scop­ic exocrine glands in the skin that secrete an oily or waxy mat­ter, called sebum, to lubri­cate and water­proof the skin and hair of mam­mals. In humans, they are found in the great­est num­ber on the face and scalp, and are also found on all parts of the skin except the palms of the hands and soles of the feet. The type of secre­tion of the seba­ceous glands is referred to as holocrine. In the eye­lids, mei­bo­mi­an glands, also called tarsal glands, are a type of seba­ceous gland that secrete a spe­cial type of sebum into tears. Fordyce spots are ectopic (mis­placed) seba­ceous glands found usu­al­ly on the lips, gums and inner cheeks. Are­o­lar glands sur­round the female nip­ples. Preputial glands also known as Tyson’s glands are found in the gen­i­tals of both sex­es of mice and rats. There are sev­er­al relat­ed med­ical con­di­tions, includ­ing acne, seba­ceous cysts, hyper­pla­sia and seba­ceous ade­no­ma. These are usu­al­ly attrib­ut­able to over­ac­tive seba­ceous glands which pro­duce an excess of sebum.