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The pan­creas is a glan­du­lar organ in the diges­tive sys­tem and endocrine sys­tem of ver­te­brates. In humans, it is locat­ed in the abdom­i­nal cav­i­ty behind the stom­ach. It is an endocrine gland pro­duc­ing sev­er­al impor­tant hor­mones, includ­ing insulin, glucagon, somato­statin, and pan­cre­at­ic polypep­tide which cir­cu­late in the blood. The pan­creas is also a diges­tive organ, secret­ing pan­cre­at­ic juice con­tain­ing diges­tive enzymes that assist diges­tion and absorp­tion of nutri­ents in the small intes­tine. These enzymes help to fur­ther break down the car­bo­hy­drates, pro­teins, and lipids in the chyme.